I am league secretary of a mixed league and we are having our hi-lo tournament on Monday.  I have an odd number of people and I don't know what to do. 

Does anyone have any suggestions?  There is nothing in our by-laws about it and last year I used a vacancy score and that didn't work out too good. 

Any help would be greatly appreciated!

Not sure exactly what you mean, but why not have a singles tournament?

This would depend on how your league came to have an odd number of bowlers (vacancy on one team, odd number of teams, etc.). 

If it is due to the odd number of teams in a league where playing strength is an odd number of bowlers (three or five), then doing a high-low would be difficult.  If not everybody cashes, you could give the middle person the option of (a) not participating or (b) pair him/her up with both the person above and the person below him/her. 

If some teams in your league have extra roster players, and is of the four-person variety (like mine), you would have to have those declare their line-up for high-low night the week prior to bowling, so that the secretary (presumably you) can properly calculate the pairings based on those actually participating. 

The "everybody cashes" scenario usually is initiated by having as little as $1.00 added to the weekly payment.  This dollar is "earmarked" for the high-low doubles, where everybody gets something back.  In my scenario, this generates a prize fund of $1,280.  First place is $250, all the way down to $20 per team for the lower-finishing teams.  Absentees are NOT penalized -- in other words, if your partner is missing, you get their average straight up for high-low purposes only.  Handicap is figured at 100% from the highest team. 

Hope these off-the-wall suggestions help.